Luco dei Marsi is a comune and town in the province of L'Aquila in the Abruzzo region of central-eastern Italy.

The town was probably founded by the Roman Emperor Claudius to house workers in the drying of the Lacus Fucinus (Lake Fucino).

The name derives from a nearby wood, Lucus Angitiae, "Sacred Grove of Angitia", referring to a divine sorceress of the Marsi Italic tribe.

During the Middle Ages it was a fief of the D'Aquino and then of the Colonna family.

This Abruzzo location article is a stub.