Her film, stage and television roles have included appearances in Pride and Prejudice (1995) and sitcom Game On.
Briers played Mary Bennet in the BBC's television adaptation of Pride & Prejudice (1995).
In 2007, Briers appeared in Some Kind of Bliss, a one-woman play by Samuel Adamson at the Trafalgar Studios, a role she reprised in the 2008 Brits off Broadway season.
She appeared in the BBC drama Einstein and Eddington (2008) and a West End revival of Chekhov's Ivanov.
[citation needed] In 2011 she appeared in BBC Four's Twenty Twelve first as Anna Mitchell, one of the three candidates for the post of curator of the Cultural Olympiad, then with her face blurred as Laura, Ian Fletcher's wife.