He graduated from high school in Budapest and studied violin, composition and music history at the conservatory there.
In 1888 he finally settled in Vienna and worked for various Viennese newspapers as music critic.
He advocated the nationalization of the Konservatorium Wien Privatuniversität, the founding of the Volksoper and the construction of the Konzerthaus and was a well-known promoter of young talent.
Karpath worked with numerous composers, including Johannes Brahms, Pietro Mascagni, Giacomo Puccini, Gustav Mahler and his wife Alma, Max Reger and Siegfried and Cosima Wagner as well as musicians, such as Arthur Nikisch, Hans Richter and Felix Mottl.
On 10 September 1936, Karpath was buried in an honorary tomb at the Wiener Zentralfriedhof (group 30D, series 1, No.