Luigi Poggi (25 November 1917 – 4 May 2010) was an Italian Roman Catholic prelate, nuncio, and spymaster who led The Entity, the foreign intelligence service of the Holy See.

Made titular bishop of Forontoniana in 1965 upon assignment as nuncio, Poggi officially served as papal representative to several African nations before being reassigned to Europe to advance Paul VI's Ostpolitik policy of rapprochement to the Eastern Bloc.

Poggi was elevated to cardinal in 1994 and ended his career in Rome, as nuncio to Italy and finally as head of the Vatican Library and Secret Archives.

On 1 August 1973, Pope Paul assigned him a special role as a nuncio responsible for improving relations with Poland, Hungary, Czechoslovakia, Rumania and Bulgaria.

After ten years as a cardinal deacon he took the option to be elevated to Cardinal-Priest of San Lorenzo in Lucina on 24 February 2005, just weeks before the death of Pope John Paul.