Influenced by the avant-garde members of the surrealist movement, his first work titled "Luna Park" was published in 1923 and dedicated to the Guatemalan writer Enrique Gómez Carrillo (1873–1927).
Decades later in 1991 Cardoza wrote a book entitled Miguel Ángel Asturias, Casi Novela (Ediciones Era) about their time in Paris during the 1920s and 1930s that earned him the 1992 Mazatlan Literature award in Mexico.
Luis Cardoza was appointed Consul General of Guatemala in New York City under the Guatemalan government of Lázaro Chacón but in the early 1930s left the job and his country because of the dictatorial rule of new President Jorge Ubico.
He chose to live in self-imposed exile in Mexico City where he became a member of the Liga de Escritores y Artistas Revolucionarios (LEAR), an artist and intellectual group (Renato Leduc, Federico Cantú.
Federico Cantú Garza Luis Ortiz Monasterio, Alfonso Reyes, Jose Moreno Villa) that at the time had considerable influence on the artistic, cultural and political life of Mexico.