[4] García made his postseason debut in Game 5 of the American League Championship Series (ALCS) against the Tampa Bay Rays.

[7] Following the regular season, the Houston chapter of the Baseball Writers' Association of America (BBWAA) named García as the Astros' Rookie of the Year.

[8] He finished second to Randy Arozarena of Tampa Bay in the American League Rookie of the Year balloting, receiving two first-place votes.

However, he adjusted his mechanics and started Game 6 on October 22 which resulted in a gem; in 5+2⁄3 innings, he struck out seven with one walk and one hit while helping to shut out the Boston Red Sox.

Thus, García tied the club record for the longest number of innings pitched without allowing a hit in postseason history, equaling Brandon Backe's performance in the 2004 NLDS.

[13] On May 29, García retired the first 13 Seattle Mariners batters until a walk to Eugenio Suárez and did not allow the first hit until Luis Torrens singled leading off the sixth inning as the Astros eventually won, 2–1.

[20] On September 19, García started the first five innings and won a 4–0 shutout of the Tampa Bay Rays to clinch a fifth American League West division title for the Astros over the previous six seasons.

The game had remained scoreless for an unprecedented 17 innings until rookie Jeremy Peña homered in the top of the 18th to eventually win it for the Astros, 1–0, in the longest shutout in postseason history.

[27] García did not play for Houston in 2024, making two rehabilitation appearances for the rookie-level Florida Complex League Astros and Double-A Corpus Christi Hooks.

He made his WBC debut during Venezuela's opening game of the tournament and in Pool D play, pitching three innings versus the Dominican Republic.