Luis Sánchez Duque (born 13 November 1956) is a Spanish football manager.
He achieved a promotion to Segunda División in his first season in charge, but was sacked in May 1995.
In the 1997 summer he was named Albacete Balompié manager, but was relieved from his duties in October.
In December 1999, after one season back at Leganés, Sánchez Duque was appointed at the helm of CD Toledo.
On 23 December 2000, Sánchez Duque was appointed Córdoba CF manager.