Luis Gustavo Santos Paulino (born February 11, 1991) is a Dominican professional baseball pitcher who is a free agent.

Assigned to the Dominican Summer League Pirates, he pitched to a 2–1 win–loss record, 2.70 earned run average (ERA), and 23 strikeouts in 231⁄3 innings.

[1] In 2012, he played for both of Pittsburgh's DSL affiliates, and posted a combined 6–3 record, 2.44 ERA, and 74 strikeouts in 622⁄3 innings pitched.

[1] During the offseason, Santos was traded, along with Luis Rico, to the Kansas City Royals for Clint Robinson and Vin Mazzaro.

[2] He split the season between the Rookie-level Burlington Royals and the Rookie Advanced Idaho Falls Chukars.

[1] Santos began the 2014 campaign with the Single-A Lexington Legends, and was promoted to the High-A Wilmington Blue Rocks at mid-season.

[1] Santos continued his progression through the Toronto minor league system, spending the majority of 2017 with the Triple-A Buffalo Bisons.

[7] On December 4, Santos signed a minor league contract with the Blue Jays that included an invitation to spring training.