He sold a number of works in Buenos Aires, and soon obtained commissions for portraits, signing "Luis De Servi".
He also decorated the entrance rotonda, depicting the primitive life of the Argentines, of the Museo de La Plata.
He linked up with Michele Marcucci and Domenico Martinelli, to fresco 12 lunettes in the arches of the choir in the city cemetery.
In 1893, he travelled to Paris to paint portraits for the Argentine Augusto Belin Sarmiento, but also gained local commissions.
He returned to Italy to paint the apse of the church of Santa Maria degli Angeli ad Alassio.
In 1898, he painted the decorations for the piano room of the house of Giacomo Puccini in Torre del Lago.
In 1910, De Servi returned to Buenos Aires to fresco the ceiling of the Presidential room in the Palazzo del Governo, and also painted panels depicting L'Italia al Mar del Piata for the Bank of Italy and Rio de La Piata.
In 1924, De Servi wrote an open letter to the "Giornale d'Italia", criticizing the paper's confrontation of the government.