Luisa María Alcalde Luján (born 24 August 1987) is a Mexican politician who is the president of the National Regeneration Movement (Morena).

[7] She became politically involved in 2005 in support of Andrés Manuel López Obrador, then-Head of Government of the Federal District.

Alcalde later became head of the youth arm of the National Regeneration Movement (Morena), then a political association in support of AMLO.

[8] As a federal deputy, she accused Governor of Pueblo Rafael Moreno Valle Rosas of persecuting activists opposed to the Morelos gas pipeline.

[13] In 2023, Alcalde was appointed Secretary of the Interior, replacing Adán Augusto López, who resigned in order to run for Morena's presidential nomination in 2024.

[20] In 2024, a deepfake video of Alcalde encouraging viewers to join an investment program via Telegram spread on social media.