Luján de Cuyo is the district capital of the Luján de Cuyo Department located in the west of the Mendoza Province of Argentina.

Situated in the upper Mendoza valley, where the river is half-way through its journey from the Andes mountains to the eastern plains, many Lujan de Cuyo vineyards sit at altitudes of around 1000 m (3280 ft).

Malbec in particular is successful in Lujan de Cuyo, but the appellation also produces good Cabernet Sauvignon, Chardonnay and Torrontes.

The majority of the vineyards are on alluvial soils; sandy or stony surfaces on clay substrata.

Asociación Atlético Luján de Cuyo are a football club that currently play in the regionalised Argentine 3rd division This article about a place in Mendoza Province, Argentina is a stub.