Originally a freelance photographer, Luke Eve transitioned into directing music videos and commercials before moving into film and television.

Eve went on to direct dozens of music videos for Australian bands, including Faker,[5] Damien Leith, Small Mercies,[6] Cosima De Vito,[7] and Nikki Webster.

[12][13][14] In 2011, Eve completed work on his second TV series for SBS, SEX: An Unnatural History, produced by Matchbox Pictures and hosted by Julia Zemiro.

[4] In 2014, he created, produced, and directed the critically-acclaimed web series Low Life, a black comedy about depression starring Henry Nixon and Claire van der Boom.

[citation needed] In 2019 Eve completed production on his debut feature film, I Met A Girl, starring Brenton Thwaites and Lily Sullivan, in the United States.

During the COVID-19 pandemic in Australia, Eve, alongside María Albiñana, created, produced, directed, and acted in one of the world's first multi-national lockdown series, CANCELLED.