Lupșa (German: Wolfsdorf; Hungarian: Nagylupsa) is a commune located in Alba County, Transylvania, Romania.

The commune is located in Țara Moților, on the slopes of Muntele Mare to the north and the Metaliferi Mountains to the south.

The area has a specific mountain relief developed on crystalline schists and metalliferous rocks.

In 1978, the communist regime opened the Roșia Poieni copper mine near Geamăna, which at the time had over 1,000 residents.

In 1986, production from the mine caused the formation of a muddy lake, which gradually submerged almost the entire village.