The appellation is located on the right bank of the Garonne and Dordogne rivers, about 45 kilometres (28 mi) from city of Bordeaux or 9 kilometres (5.6 mi) from the medieval village of Saint-Émilion.
The terroir of Lussac is characterized by the diversity of its soils, distributed between the plateaus, the sides of the hills, and small valleys.
To the south-east, the slopes are clayey-limestone, similar in nature to those in the Saint-Emilion appellation.
To the west, there is an elevated gravel and sandy-gravel plateau, not very wide, and to the north, cold clayey soil or heavy clay is predominant.
To the east, the subsoil consists of limestone beds which made excellent quarries for extracting soft building stone.