[3] The unincorporated communities of East Millsboro, La Belle, Hiller, Isabella, Luzerne, Dutch Hill, Maxwell, Allison, Alicia, East Fredericktown and Penncraft are located within the township.

La Belle, Luzerne, Dutch Hill, Maxwell and East Fredericktown are served by the post office in La Belle and thus have the same ZIP code (15450), as does SCI Fayette, a Pennsylvania state prison located next to East Fredericktown.

The westernmost point in Fayette County is in Luzerne Township along the Monongahela south of East Millsboro.

[3] The Mon–Fayette Expressway crosses the northern part of the township, with access from Exit 26 south of Hiller.

26.7% of all households were made up of individuals, and 16.4% had someone living alone who was 65 years of age or older.