The lycée Champollion or "Champo" is a French secondary school and higher education establishment in Grenoble, at 1 Cours Lafontaine, one block from the Place Victor Hugo.

In 2017, 350 pupils were studying in Seconde, 256 in Première, 232 in Terminale and 982 in CPGE, at the lycée Champollion.

The decision to build a second lycée in the town and to name it after the linguist Champollion was taken in 1880.

Designs were commissioned from the architect Joseph Auguste Émile Vaudremer and the building was completed in October 1887.

List of languages in alphabetical order: In 2007, about 800 students were in classes préparatoires at the lycée Champollion.