The Lycoming GO-480 is a family of six-cylinder, horizontally opposed fixed-wing aircraft engines of 479.6 cubic inch (7.86 L) displacement, made by Lycoming Engines.

The engine is a six-cylinder version of the four-cylinder Lycoming O-320.

GO-480 series engines are installed on a number of different aircraft types.

[1] Their main competitive engines are the Continental IO-520 and IO-550 series.

[2][3] There are also numerous engine suffixes, denoting different accessories such as different manufacturers' carburetors, or different magnetos.