[2] Born in Rome and the daughter of silent film actor and director Carlo Simoneschi, she began her acting career when she was very young in Camillo Pilotto's stage company; in the early 1930s she made her film debut, but her inconspicuous physical appearance did not help her in front of the camera.
[3] From the early 1940s until the first half of the 1960s, Simoneschi became one of the most prominent Italian voice actresses, lending her voice to almost all the greatest Hollywood and European divas which include Barbara Stanwyck, Susan Hayward, Ingrid Bergman, Marlene Dietrich, Joan Crawford, Olivia de Havilland, Vivien Leigh and Maureen O'Hara.
In Simoneschi's animated roles, she provided the Italian voices of the Blue Fairy in Pinocchio, Flora in Sleeping Beauty, Madam Mim in The Sword in the Stone and the Fairy Godmother in the 1967 redub of Cinderella.
One of Simoneschi's main skills was that of being able to adapt very well to the different acting styles of the numerous actresses to whom she lent her voice.
[5] In the spring of 1980 the then President of Italy Sandro Pertini named her Knight of the Republic for her artistic merits.