Redington resigned as Rutland's postmaster because he relocated to New York City, where he continued to practice law and took part in politics as a member of the Tammany Hall Democratic organization.

[1] George Redington was active in the lumber and real estate businesses, served as a local judge, and was a member of the New York State Assembly.

[11] In partnership with Albert H. Tuttle, from July to December 1873 Redington also held a one-third ownership share of the Rutland Herald newspaper, for which he prepared frequent editorials on politics and current events.

[15] Despite holding this affiliation during the period of more than 100 years when Republicans won every statewide election, Redington served in several party positions and attained electoral success at the local level.

[15] As a supporter of Grover Cleveland's successful 1884 presidential campaign, Redington was rewarded in July 1885 with appointment as Rutland's postmaster, and he resigned his judgeship.

[33] In addition, he was involved in several business ventures, including serving on the board of directors and as president of the New England Fire Insurance Company.

[41] In addition to practicing law, he was an organizer of the National Homestead Company, an investment and home mortgage firm, of which he was president.

[46] His support for a bill that would have formed a private utility company for Astoria, Queens caused the leaders of Tammany Hall to request his resignation from the organization.

[47][48] In May 1898, Redington was appointed to thee board of directors of a newly-formed business venture, the Alaska Sunrise Gold Mining Company.

[49] As a result of his falling out with Tammany Hall, he was not renominated for the Assembly in 1899, and he subsequently attempted to form a competing organization, the Tecumseh Club.

[51] During the 1900 United States presidential election, he announced that Democratic nominee William Jennings Bryan's support for bimetallism with respect to U.S. currency, the major economic issue of the time, had caused him to endorse incumbent Republican William McKinley, a supporter of the gold standard.

[53] During the rest of the campaign, he made speeches on behalf of Seth Low, the mayoral candidate of Republicans and anti-Tammany Democrats.

[55][56] During the 1904 United States presidential election, Redington supported Democratic nominee Alton B. Parker and made speeches on his behalf in New York and Vermont.

[57][58] In 1906, Redington was a supporter of Charles Evans Hughes, the Republican nominee in the for governor, and made campaign speeches on his behalf.

[61] In August 1911, Redington was the victim of a home robbery; news accounts indicated that the thief or thieves knew enough about tableware to steal only items of solid silver, which were worth about $100 (about $3,100 in 2024).

[62] In the 1912 United States Presidential Election, Redington backed Woodrow Wilson and was a campaign speaker at events in New York City and on Long Island.

[63] Redington continued to remain active as an attorney and was residing in and practicing law in Flushing, Queens when he died at his home on October 18, 1925.