[2]: 849  People with this hereditary condition have a double row of eyelashes, which is called distichiasis, and a risk of swollen limbs due to problems in the lymphatic system.

[3] It is estimated that only 1⁄4 of diagnosed individuals did not inherit the condition but rather acquired the syndrome via a de novo mutation.

Symptoms that have been noted in some but not all cases include cysts, light sensitivity, cardiac defects, cleft palate, and eye problems such as astigmatism and cornea scarring.

In addition to Sanger sequencing, Multiplex Ligation Probe Amplification (MLPA) can be used to determine if  duplications and deletions in  FOXC2 are present in an individual, making it a practical testing mechanism.

[9] As a result, there are few syndrome management techniques: Symptoms of distichiasis can be minimized via eyelash plucking, electrolysis and other various treatments.