Lyons is a city in Toombs County, Georgia, United States.

[6] In 1905, Lyons was designated seat of the newly formed Toombs County.

U.S. 1 runs north-south through the center of town, leading north 12 mi (19 km) to Oak Park just south of its junction with Interstate 16 and south 31 mi (50 km) to Baxley.

Other highways that run through the city include Georgia State Routes 152, 178, and 292.

As of the 2020 United States census, there were 4,239 people, 1,607 households, and 1,013 families residing in the city.