Lyskovo (Russian: Лы́сково) is a town and the administrative center of Lyskovsky District in Nizhny Novgorod Oblast, Russia, located on the southern side of the Volga River (since the 1980s, forming the Cheboksary Reservoir), opposite the mouth of the Kerzhenets River, 90 kilometers (56 mi) southeast of Nizhny Novgorod, the administrative center of the oblast.

[citation needed] In 1686, Lyskovo was granted by the Russian government to the émigré Georgian monarch Archil of Imereti.

Upon the extinction of his family, the village passed to Princes Gruzinsky, a related line of Georgian royalty who arrived to Russia in 1724.

That family owned the village until the death of Prince Georgy Gruzinsky in 1852.

From 1749 to 1808, the Lyskovo estate housed St. Nino's Cross, the principal relic of Georgian Christianity.