Initially it was part of Narre Warren but was named Lysterfield in 1874 when land was set aside for a primary school.

Further along that road is the City of Knox Avenue of honour, which was first planted in 1918–19 in recognition of First World War veterans.

The most common non-English languages spoken at home include Mandarin (3.6%), Greek (1.6%), Italian (1.5%), Arabic (1.2%), and Sinhalese (1.1%).

[1] Lysterfield is also a place where people raise alpacas, and grow many vegetables, including a large sprout farm.

The centre of Lysterfield reflects its rural status, with a farm shop and a petrol station, which is advertised as 'prime land'.