The Mégiscane Lake sits in the municipality of Senneterre (parish), in La Vallée-de-l'Or Regional County Municipality (RCM), in the administrative region of Abitibi-Témiscamingue, in Quebec, in Canada.

This lake is made in length (from south-west to north-east), with three important enlargements: The toponym "Mégiscane" is of Algonquin origin and refers to a river, a lake, a dam and a locality.

Testimonies of the time reveal that the Algonquins were fishing at the line intensively on the Mégiscane River.

This toponym includes several spellings according to the explorers' reports: Megiskan, Métiskan and Métiscan.

[2] The toponym "Lac Mégiscane" was inscribed on December 5, 1968, at the Bank of Place Names of the Commission de toponymie du Québec.