Mérignac (French pronunciation: [meʁiɲak]; Occitan: Merinhac) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.

The 20th-century historian Robert Étienne (1921–2009) was born in Mérignac.

It is the largest suburb of the city of Bordeaux and adjoins it to the west.

Mérignac is the site of Bordeaux International Airport.

The commune has about 5,000 students in the primary and secondary schools in its city.