After that, she was called by the president of the Republic Virgilio Barco Vargas to occupy the Viceministry of Mines and Energy and later the Viceminister of Justice.
[1] In September 1989 she assumed the position of Minister of Justice and Rights, being the first woman in Colombia to do so; by that time she was the eighth designated person in this department in the last three years, due to the constant threats of the drug traffickers on whom she was exercising such charges.
De Greiff was in charge of the signing of the treaty of extradition to the United States of drug traffickers, the fact that it occurred after the death of the presidential candidate, Luis Carlos Galán.
The City Mayor of Bogotá Samuel Moreno Rojas designated, in January 2008, De Greiff as the District Secretary of Economic Development, being one of its main goals the creation of a similar structure to the one she was managing, with the name of Capital Bank.
Born in Bogotá, D.C., Colombia on 6 November 1956, she is the eldest daughter of Gustavo de Greiff Restrepo and Inés Lindo Koppel.