Mørkefjord was named by the 1906-1908 Denmark expedition, which established a second weather station at Mørkefjord, in order to compare meteorological observations data with those taken at Danmarkshavn .

They built their base hut and repaired their ship "Gamma" at a place by the fjord's shores.

There are remains of Inuit sites at the mouth of the fjord.

This fjord is located east of Danmarkshavn in Daniel Bruun Land.

Kalvenø island is located off its mouth in northern Dove Bay.