It is located between the two Mücke districts of Flensungen and Merlau, 28.9 kilometres from Gießen on the Vogelsberg Railway (Vogelsbergbahn), which continues to Fulda.

In the middle of March 1945, a train carrying a 10.5 centimetre anti-aircraft gun, a two-centimetre quadruple anti-aircraft gun along with crew and ammunition wagons stood on a track of Mücke station and a train carrying people to a concentration camp stood on a different track.

Since the timetable change 2011/2012 on 11 December 2011, passenger services have been operated by the Hessische Landesbahn GmbH (HLB) with LINT 41 diesel multiple units.

The route from Hungen ran along the eastern side of the entrance building (now used as a commuter parking area) and joined the Vogelsberg Railway at the 29.1 km mark (approximately at the location of the existing signal).

[6] Mücke station is served by several bus routes that run through the municipality and the individual districts, all operated by Verkehrsgesellschaft Oberhessen (VGO).