Müller glia

[3] They are shown to be critical to the development of the retina in mice, serving as promoters of retinal growth and histogenesis, via a nonspecific esterase-mediated mechanism.

[5] Studies using a zebrafish model of Usher syndrome have implicated a role for Müller glia in synaptogenesis, the formation of synapses.

As such, they have been shown to serve as important mediators of neurotransmitter (acetylcholine and GABA specifically) degradation and maintenance of a favorable retinal microenvironment in turtles.

[10] Studies of the regenerative properties of Müller glia in both the zebrafish[11][12] and the chicken[13] retina have been performed, with the exact molecular mechanism of regeneration remaining unclear.

[14] Studies in human models have demonstrated that Müller glia has the potential to serve as stem cells in the adult retina[15] and are efficient rod photoreceptor progenitors.