The Münster–Enschede railway is a 64 km long, continuous single-track and non-electrified branch line from Münster via Gronau in the German state of North Rhine-Westphalia to Enschede in the Netherlands.

The Münster-Enschede Railway Company (Münster-Enscheder Eisenbahn-Gesellschaft, MEE) planned the line and started its construction, but its completion was carried out by the Royal Westphalian Railway Company (Königlich-Westfälische Eisenbahn, KWE), which was funded by the Prussian government.

In 1870, the MEE received a concession to build a new line to the Netherlands and started construction from Münster to Enschede.

In the early 1990s the idea developed to build a Euroregion cycling path on the closed section.

A public agreement to restart passenger services between Enschede and Gronau was signed on 18 November 1998.

There are additional late connections on Friday and Saturday nights and on the eve of public holidays.

After a temporary suspension of the tender on 28 April 2010, it was announced that DB Regio Westphalia has been awarded the contract for this network.

As the use of the trains has been on the rise in recent years, which is attributed to commuter traffic to the university located in Steinfurt and the attractiveness of the modernisation of the line, services are approaching the limits of their capacity.

In September 2012, the council of the Münster district published a list of rail projects as a submission to the new Federal Transport Infrastructure Plan (Bundesverkehrswegeplan), which is intended to be finalised in 2015.