She is best known for her role as Nahomi in the thriller Deep Fear and her cameo as Sophia Loren in House of Gucci.

During her career, Ghenea did fashion shows in Romania, Italy, Germany, Japan, Austria, Spain, France and South Africa, and appeared in several advertisements including Peroni, New Yorker and Quelle.

[10] In 2010, Ghenea appeared in the sixth edition of the Italian talent show Ballando con le Stelle, her partner becoming dancer Simone Di Pasquale.

With the Italian actor Gabriel Garko,[12] Ghenea co-hosted and supported Carlo Conti for the 2016 edition of Sanremo Music Festival.

[20] In March 2017, she announced on social networks she was pregnant with her first child with the Romanian millionaire Matei Stratan.