Měcholupy (German: Michelob) is a market town in Louny District in the Ústí nad Labem Region of the Czech Republic.

The southern part lies in the Rakovník Uplands and includes the highest point of Měcholupy at 433 m (1,421 ft) above sea level.

[3] Among the owners of the village were King Vladislaus II, the Sekera od Sedčice family, and members of the dynasties of Kolowrat and Lobkowicz.

[4] At the end of the 17th century, during the rule of Karl of Paar, the local fortress was rebuilt into a Baroque castle with a chapel.

[3] In 1860, Anton Dreher bought Měcholupy, established a new brewery and had rebuilt the castle into its current appearance.