TNMGRMU) is a government medical university situated in Guindy in the southern part of the city of Chennai, Tamil Nadu, India.

The members of the High Level Committee, consisting of Dr. S. Arumugam, Dr. M. Natarajan, and Dr. S. Kameswaran, submitted the proposals to the former Chief Minister of Tamil Nadu M. G. Ramachandran in the presence of H. V. Hande, former Minister for Health and Family Welfare Department of Tamil Nadu, on 5 July 1983 to start a separate medical university in Tamil Nadu.

[1] The Tamil Nadu Medical University Act, 1987 received the assent of the former President of the Republic of India R. Venkataraman on 24 September 1987.

The Chancellor and Pro-Chancellor of the university are the Governor and the Minister of Health and Family Welfare of Tamil Nadu, respectively.

The Vice-Chancellor is the main academic officer and administrator in the everyday functioning of the university and is appointed by the Government of Tamil Nadu.