TPT's offices and studio facilities are on East 4th Street in downtown Saint Paul; KTCA-TV and KTCI-TV transmit from the KMSP Tower in Shoreview, Minnesota.

KTCA (channel 2) began broadcasting as the first non-commercial public television station in the state on September 16, 1955, from a shabby, WWII wooden barracks-type structure on the University of Minnesota Agricultural Campus.

The studios and offices were moved in the 1960s to what was known as the Minnesota Statehood Centennial Memorial Building for Education Television, at 1640 Como Avenue in Saint Paul.

On September 16, 1999, the stations began their first digital television broadcasts, 10 years after moving to 172 4th Street East in downtown Saint Paul.

In December 2005, the organization began distributing many of its productions online, making programs available through iTunes, Google Video, and Yahoo!

The Minnesota Channel (TPT MN) is a full-time statewide network originating at Twin Cities Public Television and carried on digital subchannels of nine stations.

In 2002, TPT began setting aside time on KTCI for the "Minnesota Channel", an evening dedicated to local and regional related programming, which expanded to a full-time digital subchannel on September 16, 2004.

[13] It continued to use both KTCA-DT and KTCI-DT's transmitter, but shut down the separate tpt17 service and unified all over-the-air channels as virtual subchannels of 2.