The ride's purpose is to raise money for multiple sclerosis, a chronic disease that affects the central nervous system.
In October 2015, the threat of Hurricane Joaquin prompted New Jersey governor Chris Christie to declare a state of emergency.
The large scale of the event precluded the possibility of postponing, although the 2015 ride raised nearly $4.4 million by the time it was cancelled.
At the finish line, a variety of events are held on the boardwalk in Ocean City, one of the most popular family vacation spots in the United States.
All of the donations received go to the National MS Society for research to find a cure for multiple sclerosis, and provide services for the 11,000 local people living with the disease.