MS Lady of Mann (II) was a side-loading car ferry built in 1976 for the Isle of Man Steam Packet Company and operated on the Douglas–Liverpool crossing.

She was the second vessel in the line's history to be so named, the first being the company's "centenary steamer", RMS Lady of Mann which entered service in 1930.

Based on the earlier Mona's Queen, she was 2 inches (51 mm) smaller and had 12-cylinder diesel engines, compared to her elder sister's 10.

Problems at the end of August led to Lady of Mann returning to service, and a drop in passenger numbers, who had been tempted by the SeaCat's high speed.

In 1996, the Steam Packet Company was bought by Sea Containers and all vessels in the fleet were painted in the new owner's blue livery.

The winter of 1999 led to a long programme of sailings for Lady of Mann, with the fastcraft and Ben-my-Chree unable to operate.

During the winter of 2000–01, Lady of Mann maintained the company's Douglas–Liverpool services, before entering Cammell Laird yard for a refit to comply with the latest SOLAS regulations, which included a new fast response craft on her starboard boat deck.

Due to the foot and mouth outbreak, Lady of Mann's 25th anniversary cruise to her birthplace in Troon was cancelled, to prevent the disease reaching the island.

During Ben-my-Chree's major refit in 2004, sailings were covered by Lady of Mann and the chartered freight ship Hoburgen.

The island had a record TT season in 2004 after which, Lady of Mann went out once again on charter to the Azores, returning for the winter schedule.