The Society publishes a variety of scientific journals, textbooks, and other educational materials related to microbiology and infectious diseases.

"[2] The society seeks to accomplish this mission through: ASM has more than 36,000 members, including researchers, educators and health professionals.

"[6] Activities of the academy include electing new members, convening colloquia, and managing the ASM Awards and Prize program.

Members of the AAM are elected through an annual peer-reviewed process based on their records of scientific achievements that have advanced microbiology.

The AAM holds colloquia, sometimes in conjunction with other scientific societies, on topics pertinent to public interests and the expertises of its members.

This award, aimed to attract more under-represented minorities to the field, is given to a mid-to-senior level scientist who is both highly accomplished and an "outstanding" speaker.

[17] The American College of Microbiology (ACM) certified microbiologists and immunologists and provided accreditation of postdoctoral training programs.

Mundo de los Microbios hosted by Gary Toranzos, is ASM's weekly Spanish-language podcast.

Meet the Microbiologist is a podcast hosted by Julie Wolf, Ph.D., that showcases the people behind the scientific discoveries in various cutting-edge areas of the microbial sciences.

In 2011, ASM made a concerted effort to address the lack of visibility of its policy arm, specifically in promoting the interests of clinical microbiologists.

In 2018, ASM engaged members of Congress and issued statements in conjunction with Congressional hearings focusing on recent outbreaks of vaccine-preventable diseases like the measles.

In 2018, ASM advocated successfully for establishing PACCARB (President's Advisory Council for Combatting Antibiotic Resistance Bacteria) into the law (from an Obama administration Executive Order), by including language in the Pandemic and All-Hazards Preparedness and Advancing Innovation Act.

ASM convened a meeting with more than 20 stakeholder groups to discuss a collective path forward for federally-focused advocacy in support of microbiome research.