[1] The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21[2][3] throughout the Carolinas.

[4] The hospital has a rooftop helipad[5] and is an ACS verified level I pediatric trauma center, the only one in South Carolina.

[12] Officials from MUSC have said that the old building that contained the children's hospital would probably turn into offices and new care areas for adults.

[14] In May 2011 it was released that aerospace company, Boeing made a donation of $1 million to the hospital to establish a center to promote healthy eating and habits to children in South Carolina.

[15] In 2015 it was announced that tech executive Shawn Jenkins had donated $25 million to the fund for the new hospital, the same amount of the state of South Carolina.

[17][18] Planning for the new hospital started a 17 years before construction and took input from patients, families, and medical staff in the design of the new building.

[39] The hospital features an 86-bed AAP verified level 4 neonatal intensive care unit, the highest in South Carolina and surrounding states.