Mačva (Serbian Cyrillic: Мачва, pronounced [mâːt͡ʃv̞a]; Hungarian: Macsó) is a geographical and historical region in the northwest of Central Serbia, on a fertile plain between the Sava and Drina rivers.

A small northern part of Mačva region is in the Autonomous Province of Vojvodina, in the Syrmia District.

The region is named after a town of Mačva, which existed in the Medieval Ages near the river Sava.

In the first century BC, the region was conquered by the Romans, and Scordisces were pushed to the northern side of the Sava river.

Roman rule lasted until the 5th century, and the region was conquered by the Sarmatians, Huns, Goths, Gepids, Lombards and Avars.

Banovina was named after a town called Mačva, but the location of this settlement has not been clearly established in modern times.

Hungarian king Béla IV granted authority over Mačva to Rostislav Mikhailovich, a refugee Russian prince.

Between 1282 and 1316 the Serb King Stefan Dragutin ruled the Kingdom of Srem, which consisted of Mačva, Usora, Soli and some adjacent territories.

Mačva is located in the southern edge of Pannonian basin, between the Cer and Fruška Gora Mountains.

Total number of settlements in Mačva is 39, of which 37 are rural, and 2 (Šabac and Mačvanska Mitrovica) are urban.