Following the splitting of the University of East Asia into three, the Macao Polytechnic University was established in 1991, comprising a number of schools with a long history of public education operation, including the Technical School of the Chinese Affairs Bureau, the Public Administration Training Centre, the Academy of Visual Arts and the Technical School of the Health Bureau.

Every year, MPU offers various types of training programmes with attendance of over 10,000 people at all levels.

[4] On 13 February 2014, the university achieved the rating of "confidence", as a judgement of its Institutional Review conducted by the Quality Assurance Agency for Higher Education (QAA), UK.

[5] On July 29, 2022, the university was accreditedfor International Quality Review (IQR) and Institutional Accreditation (IA) by QAA, met ten standards of the European Higher Education Area (ESG), including two good practices (student research and innovation as well as its comprehensive talent cultivation model) were recognised.

[6] Most of the programmes offered by the university have gained international recognition from various review and accreditation agencies/institutions: The university is the only higher education institution in the country to receive the "APQN Quality Awards" by the Asia-Pacific Quality Network (APQN) three times: The university won the "National Teaching Achievement Award" in 2019 and 2023, making it the first and only higher education institution in Macao to receive this award twice.