The main building has a distinctive, asymmetrical, conical shape with a spiral walkway and a large atrium inside.

Galleries lead off the walkway, mainly consisting of interactive exhibits aimed at science education.

The building is in a prominent position by the sea and is now a landmark of Macau.

The center was opened in December 2009 by Chinese President and General Secretary of the Communist Party Hu Jintao.

[1] The center caught on fire on 20 November 2015, due to welding occurring on the top level of the building.