Machaonia is a genus of flowering plants in the family Rubiaceae.

Some species have been called "alfilerillo", a Spanish name for the common and well-known genus Erodium.

[3] Machaonia was named by Humboldt and Bonpland in 1806 in their book, Plantae Aequinoctiales.

[4][5] This genus name is for Machaon, the son of Asclepias in Greek Mythology.

Phylogenetic studies of DNA sequences have shown that Machaonia is paraphyletic over Neoblakea and Allenanthus.