Macksburg is a village in Washington County, Ohio, United States, along the West Fork of Duck Creek.

The village is about 28 miles (45 km) south of Cambridge, Ohio.

The subsequent oil boom peaked in 1886, but production had ceased by 1900.

26.0% of all households were made up of individuals, and 9.1% had someone living alone who was 65 years of age or older.

There were 92 housing units at an average density of 394.6 per square mile (152.4/km2).

30.0% of all households were made up of individuals, and 11.3% had someone living alone who was 65 years of age or older.

About 37.8% of families and 45.3% of the population were below the poverty line, including 72.5% of those under the age of eighteen and 21.7% of those 65 or over.