It has two sister schools, the Geschwister Scholl Gymnasium (GSG) in Düsseldorf, Germany, and the Hauibei Experimental School in the Anhui province in China and has an international student program.

In 2010 Macleod College obtained funds through the National School Pride Program to renovate its Year Seven area to an open-plan design and the Primary Schools for the 21st Century program to build a new wing for Grade 3-6 students.

Macleod College has a strong history of music education.

One in five students at Macleod College are currently involved in the music performance program Macleod College has a dedicated hairdressing training salon to deliver the VET hairdressing course.

Eleven schools in the Northern Metropolitan zone send students to Macleod College to do the course.