Macomb High School is a public four-year high school located in Macomb, Illinois, a city in McDonough County, Illinois, in the United States.

[2] The school draws students from the towns of Macomb, Bardolph, and Adair.

Macomb High School is currently Fully Recognized by making adequate yearly progress and complying with state tests and standards.

MHS made Adequate Yearly Progress in 2009 on the Prairie State Achievement Examination, a state test that is part of the No Child Left Behind Act.

[3] In 2023, the faculty was 145 teachers, averaging 16.0 years of experience, and of whom 42% held an advanced degree.