[1] The Allmusic review by Sean Westergaard awarded the album 4 stars out of 5, stating "while the Nels Cline Singers may have a new bass player and a new label, fortunately their sound has not changed.

[2] The Guardian's John Fordham rated the album 3 stars out of 5, saying, "Macroscope is a blast through warped Latin music, Hendrix freakouts, double-taking George Bensonian smoothness, electronica and grunge".

[3] Writing for All About Jazz, Matt Marshall stated "Since this is a Nels Cline album there are, of course, guitar solos of blistering beauty.

But these moments are but part of an organic progression of an ever- roiling music, a highly reactive science experiment that might generate searing fuzz guitar from undulating beats ("Red Before Orange") or rise in a back-spinning psychedelic echo ("The Wedding Band") that replicates into an annihilating vortex of amplified noise".

[5] Paste Magazine's Robert Ham called it "one of the best jazz releases of the year to date".