[4] Microcebus berthae is one of many species of Malagasy lemurs that came about through extensive speciation, caused by unknown environmental mechanisms and conditions.

[6] After its discovery in 1992 in the dry deciduous forest of western Madagascar, it was initially thought to represent a rediscovery of M. myoxinus, but comparative morphometric and genetic studies revealed its status as a new species, M.

[7] This lemur is named after the conservationist and primatologist Berthe Rakotosamimanana of Madagascar, who was the Secretary General of the Groupe d'Etudes et de Recherche des Primates (GERP) from its founding until her death in 2005.

[8] Microcebus berthae has short, dense dorsal pelage that is bicolored cinnamon and yellow ochre.

Otherwise, they can be found sleeping next to one or more lemurs, with no preference or prejudice to close relatives or members of the opposite sex.

Unlike other species of lemur, Microcebus berthae do not hibernate during the cold-dry season, instead compensating for food scarcity with a larger than average home range.

Research has also been conducted on the distribution of sleeping sites, as well as on testes size and the presence of vaginal plugs.

Study of capture rates and physiological proof reveals no evidence that M. berthae has a hibernation season, which increases the chances of sexual activity within the species.

Both of these Microcebus species have an omnivorous diet, and used the same food sources, including sugary homopteran secretions, fruit, flowers, gum, arthropods and small vertebrates (e.g. geckos, chameleons).

Because of their recent common ancestry, closely related species ought to exhibit high similarities in their use of biotic and abiotic resources, susceptibility to predators and responses to disturbances and stress.

[11] Madame Berthe's mouse lemur is an omnivore and mainly feeds on fruits and flowers of different tree and shrub species, insect secretions, gum, arthropods and small vertebrates like geckos and chameleons.

There is a high overlap in the feeding niche of both lemurs suggesting that they avoid competition by mutually excluding each other on a small scale.

[11] As of December 2019, Madame Berthe's mouse lemur is rated critically endangered by the IUCN Red List.

The main threat to this species is deforestation and habitat degradation from Slash-and-burn agriculture, illegal logging and charcoal production.

If the deforestation continues at the current rate, it is estimated that Madame Berthe's mouse lemur will become extinct within 10 years.