Madame John's Legacy is a historic house museum at 632 Dumaine Street in the French Quarter of New Orleans, Louisiana.

Behind the main building is an open courtyard, with a brick slave quarters, kitchen, and garconnière at the rear of the property probably dating to the 1820s.

[3] Although archival records point to 1788 as the date of completion for its construction, archaeological investigations suggest that the house possibly incorporates a significant amount of an earlier one built on the site circa 1730 by François Marin and occupied by his widow, the New Orleans businesswoman Elisabeth Réal, until her death in 1777.

Following the 1788 fire, owner Manuel de Lanzos instructed the American contractor Robert Jones to recycle as much brick and iron hardware as possible from his damaged house, suggesting that enough of it survived the fire to be included in the rebuilding.

Whether entirely rebuilt in 1788 or a restoration of a damaged structure, the house managed to survive the 1794 fire unscathed.