[1] It is the headquarters of Madhira mandal of Khammam division[2] and is positioned approximately 230 kilometers (140 miles) east of the state capital, Hyderabad.

Additionally, it is situated 53 kilometers (33 mi) from the district headquarters Khammam and is bordered by Andhra Pradesh state on three sides.

[4] As per the data provided by 2011 Census of India, the total population of Madhira town is 32,516.

[5] The male-female ratio per 1000 is approximately 956.12, indicating that there are slightly more females than males in the town.

The station is situated on the Kazipet-Vijayawada section of the New Delhi-Chennai main line and is an important halt for several express and passenger trains.