Madison Square–West Main Street Historic District is a national historic district located in the Susan B. Anthony Neighborhood of Rochester in Monroe County, New York.

The two sites are Susan B. Anthony Square and a former carriage company storage yard.

Located within the district boundaries is the separately listed Susan B. Anthony House.

[2] It was listed on the National Register of Historic Places in 1988.

This article about a historic property or district in Monroe County, New York, listed on the National Register of Historic Places, is a stub.